Examples of DOM Research Activities – Department of Medicine

Table of Contents

Assessment of Assay for Rapid Identification of Bloodstream Infections from Whole Blood
Latent TB prophylaxis in renal transplant patients
Impact of neonatal ophthalmic antibiotics on gut microbiome
Evaluation of Rapid diagnostics for Gram-negative bacteremia
Utility of Respiratory Virus Panels Among Sepsis Hospitalizations in the United States: A Retrospective Observational Study
Penicillin Allergy and Treatment among Emergency Department Patients with Gonorrhea
Time to Directed Therapy for MSSA Bacteremia after Discontinuation of Real-time Antimicrobial Stewardship Rapid Diagnostic Intervention

Determine Reduced – Dapagliflozin Effect on Exercise Capacity Using a 6-minute Walk Test in Patients With Heart Failure with Reduced Ejection
NODE-303 Trial – Study of Etripamil Nasal Spray for Patients with Paroxysmal Supraventricular Tachycardia
The CARILLON Trial – Assess safety and efficacy of the Carillon Mitral Countour System in treating subjects with functional mitral regurgitation (FMR) associated with heart failure, compared to a randomized control group which is medically managed according to heart failure guidelines

The Role of Sensory Innervation in β-Cell Regeneration and Function
Genetically and Anatomically Targeted Neuromodulation of Pancreatic β-Cells
Substrate and Hormonal Regulation of Gluconeogenesis
Sensory-Derived Signals Regulated Regeneration of Insulin-Producing Cells
Anatomical-Functional Mapping of Pancreatic Sensory Neuronal Circuits
Structural and Functional Mapping of Islet β-Cell Sensory Innervation
Identification of Novel Delivery Systems for Diabetic Therapeutics
Metabolomics Data Correction and Normalization Using Stable-Isotope Labeled Internal Standards
Molecular Mechanisms of Thyroid Hormone Action
Obesity, Type 2 DM; beta cell function and glycemic improvement after surgical weight loss
Peripheral leukocytes and insulin resistance
Long Term Outcomes of NIFTP/UMP Tumors
MPOWERED(TM) Phase 3 Clinical Trial of Octreotide Capsules in Patients with Acromegaly

Novel Treatments for Fatty Liver Disease (G-Protein Coupled Receptors Regulation of Obesity Induced Fatty Liver Disease)
The Armor Study – Clinical Study to Evaluate the Efficacy and Safety of Aramchol Versus Placebo in Subjects with NASH
Abbvie M14-430, M14-431, M14-433 – Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants with Crohn’s Disease

Blood Transfusion Thresholds and Cardiovascular Events
Tobacco Dependence Treatment Interventions
Physician Communication Regarding E-cigarettes
Corticosteroid dose for hospitalized COPD treatment
Improving Quality and Safety in the hospital and outpatient medical setting linked to population health management and resource allocation
Discharge and transitions of care process improvement
Point-of-care Ultrasound in Patient care Improvement and Medical Education
COVID Pandemic outcomes research
Geriatrics and End-of-Life outcomes research
Medical Informatics and Clinical Process Outcomes

COVID-19

Rutgers Corona Cohort healthcare worker study
Strategies for diagnosis and biochemical characterization of COVID-19
STOP-COVID multicenter database to characterize risk factors and treatment effects in COVID-19
Remdesivir in the treatment of moderate and severe COVID-10
Tocilizumab in the treatment of COVID-19
Hydroxychloroquine in the treatment of COVID-19

Sleep

Sleepiness, obstructive sleep apnea, and cardiometabolic health
Sex-specific differences in sleep apnea and mechanistic pathways for cardiovascular disease
The role of sleep in addiction – focus on opioid addiction
Sleep disordered breathing in patients with advanced heart failure and CF
Sleep disturbances in commercial vehicle operators
Survey identified obstructive sleep apnea as a risk factor for developing diabetes in South Asian population
Sleepiness as a modulator of disease, assessment of sleepiness, role of sleep disorders in other diseases
Circadian rhythm disorders in the ICU

Environmental Exposures and Lung Disease

Effect of ozone exposure on sepsis-induced acute respiratory distress syndrome
Effects of World Trade Center dust exposure and chronic Intermittent hypoxia on lung injury
Sleep-disordered breathing with a focus on epidemiology, pathogenesis and consequences especially in the WTC Cohort
Identifying changes in peripheral airway responsiveness after exposure to ozone exposure

Cystic Fibrosis

Long-term safety and tolerability of VX-445 in triple combination (TC) with tezacaftor (TEZ) and ivacaftor (IVA) in subjects with cystic fibrosis (CF) who are homozygous or heterozygous for F508del mutation
Cystic Fibrosis Lung Transplant Transition

Quality Improvement

Factors Impacting Outcomes In Interventional Pulmonology Procedures
Communication and Teams approach in the ICU
Impulse oscillometry utility in identifying peripheral airway disease in asthmatics
Social Determinants of Health  (SDOH) in pulmonary and CC Medicine
Global health in critical care medicine

Scleroderma

Scleroderma calcinosis
Novel therapies for scleroderma-related lung disease
Novel therapies for Raynaud and digital ulcers 
Scleroderma renal crisis
Scleroderma damage index
EICOS ES 301 Aurora Study – Phase III clinical trial to evaluate the safety and efficacy of Iloprost on the frequency of and relief from symptomatic digital ischemic episodes in subjects with systemic sclerosis
Privigen IgPro10_2001 SSc – Efficacy and Safety of IgPro10 in Adults With Systemic Sclerosis

Gout